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In-vivo monitoring of angiogenesis-inhibitory treatment effects by contrast-enhanced dynamic CT in a xenograft tumor model

RATIONALE AND OBJECTIVES: To evaluate the potential of dynamic CT enhanced by Iohexol or a novel macromolecular contrast agent, PEG(12000)-Gen4-triiodo, to monitor microvascular changes in tumors treated with the angiogenesis inhibitor bevacizumab. MATERIALS AND METHODS: Ten female nude rats with MD...

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Detalhes bibliográficos
Main Authors: Raatschen, Hans-Juergen, Fu, Yanjun, Brasch, Robert C., Pietsch, Hubertus, Shames, David M., Yeh, Benjamin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115801/
https://ncbi.nlm.nih.gov/pubmed/19346961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/RLI.0b013e31819f1b60
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