Evaluation of a Novel Macromolecular Cascade-Polymer Contrast Medium for Dynamic Contrast-Enhanced MRI Monitoring of Antiangiogenic Bevacizumab Therapy in a Human Melanoma Model

RATIONALE AND OBJECTIVES: To assess the applicability of a novel macromolecular polyethylene glycol (PEG)-core gadolinium contrast agent for monitoring early antiangiogenic effects of bevacizumab using dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI). MATERIALS AND METHODS: Athymic r...

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Main Authors: Cyran, Clemens C., Fu, Yanjun, Rogut, Victor, Chaopathomkul, Bundit, Wendland, Michael F., Shames, David M., Brasch, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874547/
https://ncbi.nlm.nih.gov/pubmed/24029057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.acra.2013.07.010
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