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Effect of chronic hyperglycemia on in vivo insulin secretion in partially pancreatectomized rats.

We have examined the effect of chronic (4 wk) hyperglycemia on insulin secretion in vivo in an awake, unstressed rat model. Three groups of animals were examined: control, partial (90%) pancreatectomy, and partial pancreatectomy plus phlorizin, in order to normalize plasma glucose levels. Insulin se...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Rossetti, L, Shulman, G I, Zawalich, W, DeFronzo, R A
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1987
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442343/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3308956/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113157
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