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Correction of chronic hyperglycemia with vanadate, but not with phlorizin, normalizes in vivo glycogen repletion and in vitro glycogen synthase activity in diabetic skeletal muscle.

Vanadate has insulin-like activity in vitro and in vivo. To characterize the in vivo mechanism of action of vanadate, we examined meal tolerance, insulin-mediated glucose disposal, in vivo liver and muscle glycogen synthesis, and in vitro glycogen synthase activity in 90% partially pancreatectomized...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Rossetti, L, Lauglin, M R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329733/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2503545/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114250
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