Novel drug candidates for blast phase chronic myeloid leukemia from high-throughput drug sensitivity and resistance testing

Chronic myeloid leukemia in blast crisis (CML BC) remains a challenging disease to treat despite the introduction and advances in tyrosine kinase inhibitor (TKI) therapy. In this study we set out to identify novel candidate drugs for CML BC by using an unbiased high-throughput drug testing platform....

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Detalhes bibliográficos
Publicado no:Blood Cancer J
Main Authors: Pietarinen, P O, Pemovska, T, Kontro, M, Yadav, B, Mpindi, J P, Andersson, E I, Majumder, M M, Kuusanmäki, H, Koskenvesa, P, Kallioniemi, O, Wennerberg, K, Heckman, C A, Mustjoki, S, Porkka, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423219/
https://ncbi.nlm.nih.gov/pubmed/25933373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2015.30
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