Human autoantibodies to poly(adenosine diphosphate-ribose) polymerase.

The chromatin-bound enzyme poly(ADP-ribose) polymerase (ADPRP) is strongly stimulated by DNA with single- or double-stranded breaks, and transfers the ADP-ribose moiety of NAD to nuclear proteins. The activation of ADPRP is important for DNA repair and replication, and also has been postulated to pl...

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Pubblicato in:	J Clin Invest
Autori principali:	Yamanaka, H, Willis, E H, Penning, C A, Peebles, C L, Tan, E M, Carson, D A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1987
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442319/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2442198/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113150
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