Strategies for the Use of Poly(adenosine diphosphate ribose) Polymerase (PARP) Inhibitors in Cancer Therapy

Treatments with Poly(adenosine diphosphate ribose) polymerase (PARP) inhibitors have offered patients carrying cancers with mutated BRCA1 or BRCA2 genes a new and in many cases effective option for disease control. There is potentially a large patient population that may also benefit from PARP inhib...

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Hlavní autoři:	Thomas Helleday, Cecilia E. Ström
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2012-12-01
Edice:	Biomolecules
Témata:	DNA repair poly(ADP-ribose) polymerase synthetic lethality cancer
On-line přístup:	http://www.mdpi.com/2218-273X/2/4/635
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