Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody

Hepatitis E virus (HEV), a non-enveloped, positive-sense, single-stranded RNA virus, is a major cause of enteric hepatitis. Classified into the family Hepeviridae, HEV comprises four genotypes (genotypes 1-4), which belong to a single serotype. We describe a monoclonal antibody (mAb), 8G12, which eq...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Gu, Ying, Tang, Xuhua, Zhang, Xiao, Song, Cuiling, Zheng, Minghua, Wang, Kaihang, Zhang, Jun, Ng, Mun-Hon, Hew, Choy-Leong, Li, Shaowei, Xia, Ningshao, Sivaraman, J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423075/
https://ncbi.nlm.nih.gov/pubmed/25793314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.34
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