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Direct Sensing and Discrimination among Ubiquitin and Ubiquitin Chains Using Solid-State Nanopores

Nanopore sensing involves an electrophoretic transport of analytes through a nanoscale pore, permitting label-free sensing at the single-molecule level. However, to date, the detection of individual small proteins has been challenging, primarily due to the poor signal/noise ratio that these molecule...

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Publicat a:Biophys J
Autors principals: Nir, Iftach, Huttner, Diana, Meller, Amit
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423055/
https://ncbi.nlm.nih.gov/pubmed/25954891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.03.025
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