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Site-specific qualitative and quantitative analysis of N- and O-glycoforms in recombinant human erythropoietin

Recombinant human erythropoietin (rhEPO) has been extensively used as pharmaceutical product for treatment of anemia. Glycosylation of rhEPO affects the biological activity, immunogenicity, pharmacokinetics and in vivo clearance rate of rhEPO. Characterization of the glycosylation status of rhEPO is...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Anal Bioanal Chem
Päätekijät: Jiang, Jing, Tian, Fang, Cai, Yun, Qian, Xiaohong, Costello, Catherine E., Ying, Wantao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422759/
https://ncbi.nlm.nih.gov/pubmed/25080026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-014-8037-8
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