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Site-specific qualitative and quantitative analysis of N- and O-glycoforms in recombinant human erythropoietin
Recombinant human erythropoietin (rhEPO) has been extensively used as pharmaceutical product for treatment of anemia. Glycosylation of rhEPO affects the biological activity, immunogenicity, pharmacokinetics and in vivo clearance rate of rhEPO. Characterization of the glycosylation status of rhEPO is...
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| Publicado no: | Anal Bioanal Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4422759/ https://ncbi.nlm.nih.gov/pubmed/25080026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-014-8037-8 |
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