Protection by recombinant alpha 1-antitrypsin Ala357 Arg358 against arterial hypotension induced by factor XII fragment.

The specificity of serpin superfamily protease inhibitors such as alpha 1-antitrypsin or C1 inhibitor is determined by the amino acid residues of the inhibitor reactive center. To obtain an inhibitor that would be specific for the plasma kallikrein-kinin system enzymes, we have constructed an antitr...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Schapira, M, Ramus, M A, Waeber, B, Brunner, H R, Jallat, S, Carvallo, D, Roitsch, C, Courtney, M
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1987
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442273/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3497179/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113108
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