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Protection by recombinant alpha 1-antitrypsin Ala357 Arg358 against arterial hypotension induced by factor XII fragment.

The specificity of serpin superfamily protease inhibitors such as alpha 1-antitrypsin or C1 inhibitor is determined by the amino acid residues of the inhibitor reactive center. To obtain an inhibitor that would be specific for the plasma kallikrein-kinin system enzymes, we have constructed an antitr...

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Библиографические подробности
Опубликовано в::J Clin Invest
Главные авторы: Schapira, M, Ramus, M A, Waeber, B, Brunner, H R, Jallat, S, Carvallo, D, Roitsch, C, Courtney, M
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1987
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442273/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3497179/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113108
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