CD8(+) T Cell Fate and Function Influenced by Antigen-Specific Virus-Like Nanoparticles Co-Expressing Membrane Tethered IL-2

A variety of adjuvants fostering humoral immunity are known as of today. However, there is a lack of adjuvants or adjuvant strategies, which directly target T cellular effector functions and memory. We here determined whether systemically toxic cytokines such as IL-2 can be restricted to the site of...

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Bibliographic Details
Published in:PLoS One
Main Authors: Wojta-Stremayr, Daniela, Neunkirchner, Alina, Srinivasan, Bharani, Trapin, Doris, Schmetterer, Klaus G., Pickl, Winfried F.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422701/
https://ncbi.nlm.nih.gov/pubmed/25946103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126034
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