Abnormal oxidant sensitivity and beta-chain structure of spectrin in hereditary spherocytosis associated with defective spectrin-protein 4.1 binding.

Hereditary spherocytosis (HS) is an inherited disorder of erythrocyte shape associated with spectrin deficiency and hemolytic anemia. In a subset of patients with the autosomal dominant form of HS, spectrin displays a reduced capacity to bind protein 4.1 and, therefore, actin; both functions that ar...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Becker, P S, Morrow, J S, Lux, S E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442269/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3611357/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113104
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