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Development of a Cell-Based Bioassay for Phospholipase A(2)-Triggered Liposomal Drug Release

The feasibility of exploiting secretory phospholipase A(2) (sPLA(2)) enzymes, which are overexpressed in tumors, to activate drug release from liposomes precisely at the tumor site has been demonstrated before. Although the efficacy of the developed formulations was evaluated using in vitro and in v...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Arouri, Ahmad, Trojnar, Jakub, Schmidt, Steffen, Hansen, Anders H., Mollenhauer, Jan, Mouritsen, Ole G.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422686/
https://ncbi.nlm.nih.gov/pubmed/25945937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125508
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