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Development of a Cell-Based Bioassay for Phospholipase A(2)-Triggered Liposomal Drug Release

The feasibility of exploiting secretory phospholipase A(2) (sPLA(2)) enzymes, which are overexpressed in tumors, to activate drug release from liposomes precisely at the tumor site has been demonstrated before. Although the efficacy of the developed formulations was evaluated using in vitro and in v...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Arouri, Ahmad, Trojnar, Jakub, Schmidt, Steffen, Hansen, Anders H., Mollenhauer, Jan, Mouritsen, Ole G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422686/
https://ncbi.nlm.nih.gov/pubmed/25945937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125508
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