Genomic characterization of mutant laboratory mouse strains by exome sequencing and annotation lift-over

BACKGROUND: Exome sequencing has become a popular method to evaluate undirected mutagenesis experiments in mice. However, the most suitable mouse strain for the biological model may be relatively distant from the standard mouse reference genome. For pinpointing causative variants, a matching referen...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Derdak, Sophia, Sabrautzki, Sibylle, de Angelis, Martin Hrabě, Gut, Marta, Gut, Ivo G, Beltran, Sergi
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Methodology Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422528/
https://ncbi.nlm.nih.gov/pubmed/25943197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1548-7
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