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Genomic characterization of mutant laboratory mouse strains by exome sequencing and annotation lift-over

BACKGROUND: Exome sequencing has become a popular method to evaluate undirected mutagenesis experiments in mice. However, the most suitable mouse strain for the biological model may be relatively distant from the standard mouse reference genome. For pinpointing causative variants, a matching referen...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Derdak, Sophia, Sabrautzki, Sibylle, de Angelis, Martin Hrabě, Gut, Marta, Gut, Ivo G, Beltran, Sergi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422528/
https://ncbi.nlm.nih.gov/pubmed/25943197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1548-7
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