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Genomic characterization of mutant laboratory mouse strains by exome sequencing and annotation lift-over

BACKGROUND: Exome sequencing has become a popular method to evaluate undirected mutagenesis experiments in mice. However, the most suitable mouse strain for the biological model may be relatively distant from the standard mouse reference genome. For pinpointing causative variants, a matching referen...

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Bibliografische gegevens
Gepubliceerd in:BMC Genomics
Hoofdauteurs: Derdak, Sophia, Sabrautzki, Sibylle, de Angelis, Martin Hrabě, Gut, Marta, Gut, Ivo G, Beltran, Sergi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422528/
https://ncbi.nlm.nih.gov/pubmed/25943197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1548-7
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