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Genomic characterization of mutant laboratory mouse strains by exome sequencing and annotation lift-over

BACKGROUND: Exome sequencing has become a popular method to evaluate undirected mutagenesis experiments in mice. However, the most suitable mouse strain for the biological model may be relatively distant from the standard mouse reference genome. For pinpointing causative variants, a matching referen...

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Vydáno v:BMC Genomics
Hlavní autoři: Derdak, Sophia, Sabrautzki, Sibylle, de Angelis, Martin Hrabě, Gut, Marta, Gut, Ivo G, Beltran, Sergi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422528/
https://ncbi.nlm.nih.gov/pubmed/25943197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1548-7
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