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Mutant forms of spectrin alpha-subunits in hereditary elliptocytosis.

Two variant spectrins have been described in hereditary elliptocytosis (HE) and pyropoikilocytosis (HPP). Both are characterized by increased susceptibility of the alpha I (N-terminal) 80-kD domain to mild tryptic digestion, yielding peptides of 46-50 or 65-68 kD (T50a and T68 in our terminology). I...

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Detalhes bibliográficos
Main Authors: Marchesi, S L, Letsinger, J T, Speicher, D W, Marchesi, V T, Agre, P, Hyun, B, Gulati, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC442218/
https://ncbi.nlm.nih.gov/pubmed/3597773
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