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Formation of diethylstilbestrol–DNA adducts in human breast epithelial cells and inhibition by resveratrol
Extensive evidence exists that the reaction of estrogen metabolites with DNA produces depurinating adducts that, in turn, induce mutations and cellular transformation. While it is clear that these estrogen metabolites result in a neoplastic phenotype in vitro, further evidence supporting the link be...
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| Publicado no: | J Steroid Biochem Mol Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4422071/ https://ncbi.nlm.nih.gov/pubmed/21896331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2011.08.009 |
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