Effect of chronic ethanol feeding on rat hepatocytic glutathione. Compartmentation, efflux, and response to incubation with ethanol.

Hepatocytes from rats that were fed ethanol chronically for 6-8 wk were found to have a modest decrease in cytosolic GSH (24%) and a marked decrease in mitochondrial GSH (65%) as compared with pair-fed controls. Incubation of hepatocytes from ethanol-fed rats for 4 h in modified Fisher's medium reve...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Fernandez-Checa, J C, Ookhtens, M, Kaplowitz, N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442201/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2885343/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113063
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