Safety and immunogenicity of a Pseudomonas aeruginosa O-polysaccharide toxin A conjugate vaccine in humans.

Lipid A-free polysaccharide (PS) isolated from Pseudomonas aeruginosa immunotype 5 lipopolysaccharide (LPS) was covalently coupled to toxin A via reductive amination. The PS-toxin A conjugate was comprised of 29.8% PS and 70.2% toxin A, possessed a molecular weight of greater than 1 X 10(6), was non...

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Библиографические подробности
Главные авторы: Cryz, S J, Fürer, E, Cross, A S, Wegmann, A, Germanier, R, Sadoff, J C
Формат: Artigo
Язык:Inglês
Опубликовано: 1987
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC442200/
https://ncbi.nlm.nih.gov/pubmed/3110215
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