Mechanisms of thrombocytopenia in chronic autoimmune thrombocytopenic purpura. Evidence of both impaired platelet production and increased platelet clearance.

Mechanisms of thrombocytopenia were studied in 38 patients with mild to moderately severe chronic autoimmune thrombocytopenia (AITP). 51Cr and 111In-labeled autologous platelet turnover studies and in vitro analysis of committed megakaryocyte progenitors (CFU-Meg) were used as independent measures o...

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Publié dans:	J Clin Invest
Auteurs principaux:	Ballem, P J, Segal, G M, Stratton, J R, Gernsheimer, T, Adamson, J W, Slichter, S J
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1987
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442198/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3597777/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113060
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