Mechanisms of thrombocytopenia in chronic autoimmune thrombocytopenic purpura. Evidence of both impaired platelet production and increased platelet clearance.

Mechanisms of thrombocytopenia were studied in 38 patients with mild to moderately severe chronic autoimmune thrombocytopenia (AITP). 51Cr and 111In-labeled autologous platelet turnover studies and in vitro analysis of committed megakaryocyte progenitors (CFU-Meg) were used as independent measures o...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Ballem, P J, Segal, G M, Stratton, J R, Gernsheimer, T, Adamson, J W, Slichter, S J
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1987
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Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442198/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3597777/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113060
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