Paroxysmal nocturnal hemoglobinuria type III. Lack of an erythrocyte membrane protein restricting the lysis by C5b-9.

The complement-mediated lysis is inefficient when complement and target cells are homologous with regard to the species. In erythrocytes from patients suffering from paroxysmal nocturnal hemoglobinuria (PNH), the species restriction is lost: PNH-erythrocytes (PNH-E) are susceptible to lysis by human...

Celý popis

Podrobná bibliografie

Vydáno v:	J Clin Invest
Hlavní autoři:	Hänsch, G M, Schönermark, S, Roelcke, D
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1987
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442194/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3597779/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113065
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!