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Hyaluronan mediates airway hyperresponsiveness in oxidative lung injury
Chlorine (Cl(2)) inhalation induces severe oxidative lung injury and airway hyperresponsiveness (AHR) that lead to asthmalike symptoms. When inhaled, Cl(2) reacts with epithelial lining fluid, forming by-products that damage hyaluronan, a constituent of the extracellular matrix, causing the release...
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| Τόπος έκδοσης: | Am J Physiol Lung Cell Mol Physiol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Physiological Society
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4421785/ https://ncbi.nlm.nih.gov/pubmed/25747964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00377.2014 |
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