TLR4 Is Necessary for Hyaluronan-mediated Airway Hyperresponsiveness after Ozone Inhalation

Rationale: Ozone is a common environmental air pollutant that contributes to hospitalizations for respiratory illness. The mechanisms, which regulate ozone-induced airway hyperresponsiveness, remain poorly understood. We have previously reported that toll-like receptor 4 (TLR4)–deficient animals are...

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Detalhes bibliográficos
Main Authors: Garantziotis, Stavros, Li, Zhuowei, Potts, Erin N., Lindsey, James Y., Stober, Vandy P., Polosukhin, Vasiliy V., Blackwell, Timothy S., Schwartz, David A., Foster, W. Michael, Hollingsworth, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
A. Airway Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868499/
https://ncbi.nlm.nih.gov/pubmed/20007931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200903-0381OC
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