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Lincomycin at Subinhibitory Concentrations Potentiates Secondary Metabolite Production by Streptomyces spp.

Antibiotics have either bactericidal or bacteriostatic activity. However, they also induce considerable gene expression in bacteria when used at subinhibitory concentrations (below the MIC). We found that lincomycin, which inhibits protein synthesis by binding to the ribosomes of Gram-positive bacte...

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Détails bibliographiques
Publié dans:Appl Environ Microbiol
Auteurs principaux: Imai, Yu, Sato, Seizo, Tanaka, Yukinori, Ochi, Kozo, Hosaka, Takeshi
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421039/
https://ncbi.nlm.nih.gov/pubmed/25819962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.04214-14
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