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Lincomycin at Subinhibitory Concentrations Potentiates Secondary Metabolite Production by Streptomyces spp.

Antibiotics have either bactericidal or bacteriostatic activity. However, they also induce considerable gene expression in bacteria when used at subinhibitory concentrations (below the MIC). We found that lincomycin, which inhibits protein synthesis by binding to the ribosomes of Gram-positive bacte...

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Bibliografiske detaljer
Udgivet i:Appl Environ Microbiol
Main Authors: Imai, Yu, Sato, Seizo, Tanaka, Yukinori, Ochi, Kozo, Hosaka, Takeshi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421039/
https://ncbi.nlm.nih.gov/pubmed/25819962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.04214-14
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