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Molecular Role of RNF43 in Canonical and Noncanonical Wnt Signaling
Wnt signaling pathways are tightly regulated by ubiquitination, and dysregulation of these pathways promotes tumorigenesis. It has been reported that the ubiquitin ligase RNF43 plays an important role in frizzled-dependent regulation of the Wnt/β-catenin pathway. Here, we show that RNF43 suppresses...
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| Udgivet i: | Mol Cell Biol |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4420922/ https://ncbi.nlm.nih.gov/pubmed/25825523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00159-15 |
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