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Molecular Role of RNF43 in Canonical and Noncanonical Wnt Signaling

Wnt signaling pathways are tightly regulated by ubiquitination, and dysregulation of these pathways promotes tumorigenesis. It has been reported that the ubiquitin ligase RNF43 plays an important role in frizzled-dependent regulation of the Wnt/β-catenin pathway. Here, we show that RNF43 suppresses...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cell Biol
Main Authors: Tsukiyama, Tadasuke, Fukui, Akimasa, Terai, Sayuri, Fujioka, Yoichiro, Shinada, Keisuke, Takahashi, Hidehisa, Yamaguchi, Terry P., Ohba, Yusuke, Hatakeyama, Shigetsugu
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420922/
https://ncbi.nlm.nih.gov/pubmed/25825523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00159-15
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