A mouse model of small-vessel disease that produces brain-wide-identified microocclusions and regionally selective neuronal injury

We developed a mouse model of small-vessel disease where occlusions are produced through endovascular injection of fluorescent microspheres that target ~12 μm diameter penetrating arterioles and can be localized in histology. Using Thy1-GFP transgenic mice, we visualized the impact of microocclusion...

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Detaylı Bibliyografya
Yayımlandı:J Cereb Blood Flow Metab
Asıl Yazarlar: Silasi, Gergely, She, Jennifer, Boyd, Jamie D, Xue, Songchao, Murphy, Timothy H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Brief Communication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420872/
https://ncbi.nlm.nih.gov/pubmed/25690472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.8
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