Blockade of P2X7 receptors or pannexin-1 channels similarly attenuates postischemic damage

The role of P2X7 receptors and pannexin-1 channels in ischemic damage remains controversial. Here, we analyzed their contribution to postanoxic depolarization after ischemia in cultured neurons and in brain slices. We observed that pharmacological blockade of P2X7 receptors or pannexin-1 channels de...

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Bibliographic Details
Published in:J Cereb Blood Flow Metab
Main Authors: Cisneros-Mejorado, Abraham, Gottlieb, Miroslav, Cavaliere, Fabio, Magnus, Tim, Koch-Nolte, Friederich, Scemes, Eliana, Pérez-Samartín, Alberto, Matute, Carlos
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420860/
https://ncbi.nlm.nih.gov/pubmed/25605289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.262
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