Effect of Lipopolysaccharide on Glucocorticoid Receptor Function in Control Nasal Mucosa Fibroblasts and in Fibroblasts from Patients with Chronic Rhinosinusitis with Nasal Polyps and Asthma

BACKGROUND: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory disease of the upper airways frequently associated with asthma. Bacterial infection is a feature of CRSwNP that can aggravate the disease and the response to glucocorticoid treatment. OBJECTIVE: We examined wheth...

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Pubblicato in:PLoS One
Autori principali: Fernández-Bertolín, Laura, Mullol, Joaquim, Fuentes-Prado, Mireya, Roca-Ferrer, Jordi, Alobid, Isam, Picado, César, Pujols, Laura
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420770/
https://ncbi.nlm.nih.gov/pubmed/25943109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125443
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