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Segregated responses of mammary gland development and vaginal opening to prepubertal genistein exposure in Bscl2(−/−) female mice with lipodystrophy

Berardinelli-Seip congenital lipodystrophy 2-deficient (Bscl2(−/−)) mice recapitulate human BSCL2 disease with lipodystrophy. Bscl2-encoded seipin is detected in adipocytes and epithelium of mammary gland. Postnatal mammary gland growth spurt and vaginal opening signify pubertal onset in female mice...

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Detalhes bibliográficos
Publicado no:Reprod Toxicol
Main Authors: Li, Rong, El Zowalaty, Ahmed E., Chen, Weiqin, Dudley, Elizabeth A., Ye, Xiaoqin
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420718/
https://ncbi.nlm.nih.gov/pubmed/25462787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2014.10.023
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