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A novel leptin antagonist peptide inhibits breast cancer growth in vitro and in vivo

The role of the obesity cytokine leptin in breast cancer progression has raised interest in interfering with leptin's actions as a valuable therapeutic strategy. Leptin interacts with its receptor through three different binding sites: I–III. Site I is crucial for the formation of an active lep...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Catalano, Stefania, Leggio, Antonella, Barone, Ines, De Marco, Rosaria, Gelsomino, Luca, Campana, Antonella, Malivindi, Rocco, Panza, Salvatore, Giordano, Cinzia, Liguori, Alessia, Bonofiglio, Daniela, Liguori, Angelo, Andò, Sebastiano
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420614/
https://ncbi.nlm.nih.gov/pubmed/25721149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12517
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