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Structure-based design of combinatorial mutagenesis libraries

The development of protein variants with improved properties (thermostability, binding affinity, catalytic activity, etc.) has greatly benefited from the application of high-throughput screens evaluating large, diverse combinatorial libraries. At the same time, since only a very limited portion of s...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Protein Sci
Main Authors: Verma, Deeptak, Grigoryan, Gevorg, Bailey-Kellogg, Chris
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420537/
https://ncbi.nlm.nih.gov/pubmed/25611189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2642
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