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Stressful genetics in Crohn’s disease

A common variant of the autophagy protein ATG16L1 is a risk factor for Crohn’s disease. But the genetic alteration is revealed only when the protein is cleaved by the enzyme caspase 3 during cellular stress.

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Dades bibliogràfiques
Publicat a:Nature
Autors principals: KASER, ARTHUR, BLUMBERG, RICHARD S.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420161/
https://ncbi.nlm.nih.gov/pubmed/24553137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13060
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