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Prospects for engineering HIV-specific antibodies for enhanced effector function and half-life

PURPOSE OF REVIEW: A wealth of recent animal model data suggests that as exciting possibilities for the use of antibodies in passive immunotherapy strategies continue to develop, it will be important to broadly consider how antibodies achieve anti-HIV-1 effect in vivo. RECENT FINDINGS: Beyond neutra...

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Bibliographic Details
Published in:Curr Opin HIV AIDS
Main Authors: Boesch, Austin W., Alter, Galit, Ackerman, Margaret E.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419828/
https://ncbi.nlm.nih.gov/pubmed/25700208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COH.0000000000000149
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