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Interaction between therapeutic interventions for Alzheimer’s disease and physiological Aβ clearance mechanisms

Most therapeutic agents are designed to target a molecule or pathway without consideration of the mechanisms involved in the physiological turnover or removal of that target. In light of this and in particular for Alzheimer’s disease, a number of therapeutic interventions are presently being develop...

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Pubblicato in:Front Aging Neurosci
Autori principali: Morrone, Christopher D., Liu, Mingzhe, Black, Sandra E., McLaurin, JoAnne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419721/
https://ncbi.nlm.nih.gov/pubmed/25999850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2015.00064
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