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Insulin Signaling in Sporadic Alzheimer’s Disease
Excessive production of β-amyloid (Aβ) peptides from proteolytic cleavage of amyloid precursor protein is believed to play a central role in the pathogenesis of Alzheimer’s disease (AD). In particular, accumulated intracellular Aβ is found in vulnerable neurons, and the soluble oligomers of Aβ pepti...
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| Publicado no: | Sci Signal |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4419569/ https://ncbi.nlm.nih.gov/pubmed/19509405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.274pe36 |
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