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Insulin-Resistant Brain State: the culprit in sporadic Alzheimer’s Disease?

Severe abnormalities in brain glucose/energy metabolism and insulin signaling have been documented to take a pivotal role in early sporadic Alzheimer’s disease (sAD) pathology. Indeed, the “insulin-resistant brain state” has been hypothesized to form the core of the neurodegenerative events that occ...

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Detalhes bibliográficos
Main Authors: Correia, Sónia C., Santos, Renato X., Perry, George, Zhu, Xiongwei, Moreira, Paula I., Smith, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056939/
https://ncbi.nlm.nih.gov/pubmed/21262392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2011.01.001
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