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Alk2 Regulates Early Chondrogenic Fate in Fibrodysplasia Ossificans Progressiva Heterotopic Endochondral Ossification

Bone morphogenetic protein (BMP) signaling is a critical regulator of cartilage differentiation and endochondral ossification. Gain-of-function mutations in ALK2, a type I BMP receptor, cause the debilitating disorder fibrodysplasia ossificans progressiva (FOP) and result in progressive heterotopic...

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Xehetasun bibliografikoak
Argitaratua izan da:Stem Cells
Egile Nagusiak: Culbert, Andria L., Chakkalakal, Salin A., Theosmy, Edwin G., Brennan, Tracy A., Kaplan, Frederick S., Shore, Eileen M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419363/
https://ncbi.nlm.nih.gov/pubmed/24449086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1633
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