Lin28 promotes the proliferative capacity of neural progenitor cells in brain development

Neural progenitor cells (NPCs) have distinct proliferation capacities at different stages of brain development. Lin28 is an RNA-binding protein with two homologs in mice: Lin28a and Lin28b. Here we show that Lin28a/b are enriched in early NPCs and their expression declines during neural differentiat...

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Dettagli Bibliografici
Pubblicato in:Development
Autori principali: Yang, Mei, Yang, Si-Lu, Herrlinger, Stephanie, Liang, Chen, Dzieciatkowska, Monika, Hansen, Kirk C., Desai, Ridham, Nagy, Andras, Niswander, Lee, Moss, Eric G., Chen, Jian-Fu
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2015
Soggetti:
Stem Cells and Regeneration
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419280/
https://ncbi.nlm.nih.gov/pubmed/25922525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.120543
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