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CD169(+) macrophages are sufficient for priming of CTLs with specificities left out by cross-priming dendritic cells

Dendritic cells (DCs) are considered the most potent antigen-presenting cells (APCs), which directly prime or cross-prime MHC I-restricted cytotoxic T cells (CTLs). However, recent evidence suggests the existence of other, as-yet unidentified APCs also able to prime T cells. To identify those APCs,...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bernhard, Caroline A., Ried, Christine, Kochanek, Stefan, Brocker, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418891/
https://ncbi.nlm.nih.gov/pubmed/25922518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423356112
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