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Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIP
Triple-negative breast cancers (TNBCs) are aggressive and lack targeted therapies. Understanding how nutrients are used in TNBCs may provide new targets for therapeutic intervention. We demonstrate that the transcription factor c-Myc drives glucose metabolism in TNBC cells but does so by a previousl...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4418882/ https://ncbi.nlm.nih.gov/pubmed/25870263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501555112 |
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