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MondoA Senses Non-glucose Sugars: REGULATION OF THIOREDOXIN-INTERACTING PROTEIN (TXNIP) AND THE HEXOSE TRANSPORT CURB
Glucose is required for cell growth and proliferation. The MondoA·Mlx transcription factor is glucose-responsive and accumulates in the nucleus by sensing glucose 6-phosphate. One direct and glucose-induced target of MondoA·Mlx complexes is thioredoxin-interacting protein (TXNIP). TXNIP is a potent...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207397/ https://ncbi.nlm.nih.gov/pubmed/21908621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.275503 |
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