MondoA Senses Non-glucose Sugars: REGULATION OF THIOREDOXIN-INTERACTING PROTEIN (TXNIP) AND THE HEXOSE TRANSPORT CURB

Glucose is required for cell growth and proliferation. The MondoA·Mlx transcription factor is glucose-responsive and accumulates in the nucleus by sensing glucose 6-phosphate. One direct and glucose-induced target of MondoA·Mlx complexes is thioredoxin-interacting protein (TXNIP). TXNIP is a potent...

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Bibliographic Details
Main Authors: Stoltzman, Carrie A., Kaadige, Mohan R., Peterson, Christopher W., Ayer, Donald E.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207397/
https://ncbi.nlm.nih.gov/pubmed/21908621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.275503
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